invisible

No, you have reading comprehension problems.

Smiley90

I am shocked, SHOCKED that anti-vaccine articles shared on FT by usually the same 1-2 posters turned out to be based on bad data. Absolutely shocked. Just something to keep in mind for everyone reading a "fact-based" thread that not all posts are without an agenda.

GadgetFreak

No, I don’t think I do. I went back and read it again and I read it the same way.

invisible

Carry on.

Boggie Dog

I'm one of those who are eligible and have received the Pfizer COVID third dose booster. I've seen reports that Pfizer vaccine antibodies wane after X time with the two dose regime. Would the same be true for three doses, does it really matter, or do we not yet know the answer?

corporate-wage-slave

We don't absolutely know the answer but the effect should be very similar to dose 2. Which is a daily increase in antibody response, more or less straight line, with after 10 days a pretty hefty extra response, then the line slightly flattens - still going upwards - and peaks around 24 days. Flat lines from there, for at least a while (and this is the stage we know least about). Every person is different, faster if you are younger, slower and less marked if you are older or your immune system is less responsive. The big difference, though, is that you should still have a reasonably good level of antibodies from dose 2, so this should be all at a reasonably high starting platform. No night clubs for the next 2 weeks please, as I say to my octogenarian patients. They all look horrified.

exp

We should know from Israel around January or February. They started giving boosters in July?

So we'll see if they have to boost again 6 months after the booster (3rd shot) though the booster shot is suppose to raise antibody levels way above the second shot, because it's 6 months later.

But in any event, it may not boost antibodies enough in the mucous linings of the nose and mouth, which would do the most to prevent infections and spread.

nk15

Israel leads the world by far in third doses but because of their relatively lower vaccination rates and high infection rates is a confusing country to follow.

I think Portugal is the country we should be studying closer, they are 1st or 2nd in vaccination rates in the world, and had a very high infection rate before vaccines. With a population of 10 million, 87% (first dose)/ and 84% fully vaccinated, and 1 million official Covid infections (and I am guessing that is an undercount), even with some double or breakthrough infections, almost every Portuguese person should by now be vaccinated, infected, or both. So, in theory, they should have herd immunity and be done with the pandemic. Their infection data seem to support that.

Edit: It turns out they militarized the vaccine rollout operation, and went from the worst in Europe in January to best in the world in September:

Naval officer wins praise for Portugal’s vaccine rollout (apnews.com)

PanAmWT

The news headline said hospitalization and death is cut by half. I know being an oral pill has huge advantages, but still would like to how that compares with remdesivir and the regeneration monoclonal antibody drugs?

Boggie Dog

To add to your data. Wife and I had Pfizer 3rd dose boosters Friday. Side effects were slight tenderness at injection site resolving Sunday, 2 days post injection. Jab #2 was site tenderness and fatigue for me. All doses Pfizer.

GadgetFreak

One of my favorite cartoons of all time. Although probably better suited arguments about whether Fords or Chevys are better than for scientific facts about a pandemic that has killed millions of people.

corporate-wage-slave

Since I wrote the first post, I too have had my Booster (I am both over 50 and a healthcare worker, but not in a risk category, I am now 6 months past dose 2, 9 months past dose 1). In my case the sequence is AZ + AZ + Pfizer. First AZ had me clobbered for a few hours with side effects, 6 out of 10 on the scale, took several doses of paracetemol, but the effects didn't last long. Second AZ I wouldn't have noticed any side effects if I wasn't looking for them, 1 out of 10. I think I took a single paracetemol dose but forgot to take a later dose. For my Pfizer booster on Satuday, which I had at 14:00 hrs, I was very tired Saturday evening, but a full day vaccinating is hard work for me. Sore arm Sunday morning, largely gone by the afternoon. Slightly fatigued briefly Sunday afternoon. 0.5 out of 10, and I didn't take paracetemol.

GUWonder

A bunch of my older relatives and their colleagues in the US medical field have gotten their boosters at the end of last month. It’s been PfizerB*3 for either most or maybe all of these thrice jabbed folk. Of the female ones who had any substantial, quickly passing side effects after the second shot, they mostly had the same or slightly stronger side effects compared with the second PfizerB shot; the male ones said it was the same as with their second shots: mostly nothing really noteworthy.

GUWonder

In Portugal, 98% of vaccine-eligible persons have been fully vaccinated. Of the entire population, it’s around 86% vaccinated.

It’s an impressive turnaround with vaccinations in Portugal.

invisible

Question to doc and CWS again.

If one is vaccinated and got Covid afterwards, which was either asymptomatic or so mild that it was detected only afterwards, how much such person should worry about future problems associated with Covid?

- can one catch Covid again and spread it to others?
- should one continue wearing masks, follow distancing rules, sanitize groceries with bleach/whatever/etc…

Basically my question is - at what point one (and the society) can say - Covid is not a threat to me and I am no threat to other due to Covid and what KPIs are necessary for such?