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Originally Posted by ahmetdouas
(Post 33265262)
Also an important question, is there really a point for fully vaccinated people to quarantine upon arrival or is it just not to discriminate against unvaccinated as it hasn't been offered to everyone yet?
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Originally Posted by itisme
(Post 33265705)
I was wondering. I did the first jab after being invited by old GP office after i got a text. After the vaccin they said: after approx 11 weeks you will get invite for second. But 'approx'. Should i now keeps 3 weeks free around the 11 week mark without going abroad just to wait and see when i get the invite? I rather want a real date already so i can plan things around it. People who booked directly on NHS site already get a second jab date set right? So why can't those who got first jab through gp's already set a date instead of 'approx 11 weeks'.?
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Originally Posted by itisme
(Post 33265705)
So why can't those who got first jab through gp's already set a date instead of 'approx 11 weeks'.?
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An update on vaccinations in England as of last Sunday, by age group and region.
https://imagizer.imageshack.com/v2/1...924/pHVGPE.png And below is the previous week. It's interesting how well the 40-44 year olds have had quite a big rise, compared to the progress of 45-49 in the previous week. All age groups over 50 years are now above 90%, and the average vaccination coverage of all England residents of 50 year olds and above is 95.71%. The UK wide figure for today is 70.75% have had one dose, 40.34% have had two doses, and next Sunday's figures will be still more impressive. https://imagizer.imageshack.com/v2/1...923/NK9QTp.png |
That’s the second AZ jab done (@ 15:40 today). Arm just as bad as last time but no other issues so far.
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Originally Posted by corporate-wage-slave
(Post 33266610)
Some GP services are giving both dates in the same invitation letter, but each GP can do things differently and one major factor is that GPs didn't know how the vaccine supply would work out, particularly for Pfizer. For June the system is going to be awash with vaccines. So depending on the specifics (vaccine type, age, location) you could be called in, or you could call in, after 8 weeks to get the second jab. There is no constraints on second jabs, so long as the 8 weeks is generally followed.
What advantages are there that you see to the wider spread between the two shots? Less need for a booster shot later? More efficacy to lessen the serious effects or mortality rates? Interesting to me because it seems there's a definite difference in philosophy between the protocols. I just want a safer world to move around in. |
Originally Posted by lwildernorva
(Post 33267323)
I'm intrigued as an American who has had no problem with where the science has guided us and who has no education or experience to guide me otherwise. But I noticed that you (and others in the UK) definitely encourage a wider spread between the two-shot vaccinations than we have in the US. I've simply followed the recommendations here but am interested in the perspective from your side of the Atlantic.
What advantages are there that you see to the wider spread between the two shots? Less need for a booster shot later? More efficacy to lessen the serious effects or mortality rates? Interesting to me because it seems there's a definite difference in philosophy between the protocols. I just want a safer world to move around in. |
what stut said :)
at the time, back in dec/jan, it seemed to be more of a policy decision by the government to get as many first shots into as many arms as possible to afford some degree of protection to as many people rather than no protection to many. i recall through the winter that we saw pharma companies and regulators in other countries saying that the vaccines have no data on the UK's 12-week approach which is why the idea was resisted by many others. by march it became evident that the gamble essentially paid off as we saw case rates, hospitalizations and deaths plummet quickly thanks to the vaccine and endless lockdown....but they remain constricted by supply which has obviously contracted a bit starting in april for a variety of reasons (row with the EU, india's block on exports, need for 2nd doses). notice how long its been since there has been any mention of how many doses are arriving into the UK since early april? meanwhile, the US had felt pressure i think around february to consider the same approach to spread out the time between doses...but this was when shots were in short supply and most states were struggling to reach enough of the older/compromised populations first. but as production and capacity quickly sped up, you saw that by april, the supply was flooded and the vast majority of americans who wanted a shot were able to book in. it is remarkable how quickly this all happened, because it fools the memory into thinking of "back when supply was tight" as being ages ago when really it was 2-3 months ago. |
It was a balance of risks in the end, and it paid off politically, and with (so far) good results, though the exact mechanisms are harder to find without a control group (unless a valid comparison can be found in similar conditions elsewhere). Remember that we have been in a long lockdown, only just easing now, which has also had an effect on community transmission. The 12-week gaps hadn't (again AIUI) been specifically tested for, but had no data to suggest it was a problem (though, of course, that is emerging now - "testing in production" as it were). There were concerns raised that a large partially-vaccinated cohort in an area with high community transmission could lead to drug resistant variants developing, but thankfully none of the UK variants during this time have been assessed to be Variants of Concern.
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24 hours on, still no side effects after my 2nd Pfizer jab. So that puts me in the bucket of no side effects from either jabs - what does that say about me as a person (medically)? ;)
In other vaccine news, typical that I get offered to do a vaccine trial the day after I've completed my full course of Pfizer! Not eligible to participate as I've been jabbed. Valneva – UK COVID-19 Vaccine Study Opening Now You have received this email because you previously registered with the NHS COVID-19 vaccine research registry. A new COVID-19 vaccine study is starting and looking for healthy adult volunteers to participate, who haven’t yet had a COVID vaccine. The study is sponsored by Valneva Austria GmbH. The major eligibility criteria are as follows: • Aged 18 years or older • Generally healthy • Not already received or have booked to receive a vaccination intended to prevent COVID-19 If you have received an approved vaccine as part of the national rollout then you will NOT be eligible to participate in this trial. If you have been offered the vaccine but was unable to take it or have not yet been offered an approved vaccine then we encourage you to continue on to our pre-screening programme below. If you take part in this study, and are under 30 years of age you will be assigned to receive the VLA2001 vaccine. If you are 30 years of age and over, you will be randomly assigned to receive either the investigational vaccine or the AstraZeneca vaccine, which is currently being administered throughout the UK as part of the national vaccine roll out. There is a two in three chance you will receive the investigational vaccine and a one in three chance you will receive the AstraZeneca vaccine. There will be no cost to you, and you will be reimbursed for your time and inconvenience. There will be a screening visit, two vaccination visits four weeks apart, and up to five further visits to attend. Study related activities will include physical examinations, COVID-19 testing and blood samples. In total, your participation is required for about 13 months. Find out if you qualify by visiting our pre-screening website at Pre-screening Questionnaire. This service is provided by Pharm-Olam, a commercial clinical trial company. You may be reimbursed for reasonable travel costs during your participation. Please note that travel to research or other healthcare appointments is considered essential travel at this time of extra COVID restrictions, and that your appointment will take place in a COVID-safe environment. This study is being run with the support of the NHS and the National Institute for Health Research, working in partnership with Valneva Austria GmbH, Pharm-Olam and Panthera. As a COVID-19 vaccine has been approved and roll out has started in the UK during the course of this study, we have put in place a process to make sure people on this trial are not disadvantaged. It is important to note that we will ideally find several vaccines to protect the whole population. Your participation in this study is still very much needed. More information can be found at www.bepartofresearch.org.uk. As a registered volunteer with the NHS COVID-19 vaccine research registry, you may have received a request to join this or another vaccine study before, and we may send you further invitations. If you haven't already applied through this link, we are still looking for volunteers like you. However, you cannot take part (meaning to receive a trial vaccine) in more than one vaccine study. Thank you for your ongoing participation in the NHS COVID-19 Vaccine Research Register. If you no longer wish to be part of this service, you can withdraw your permission at any time please visit Sign up to be contacted for coronavirus vaccine studies. Professor Adam Finn, MD, PhD Chief Invesitgator (sic) |
Originally Posted by flashware
(Post 33267880)
24 hours on, still no side effects after my 2nd Pfizer jab. So that puts me in the bucket of no side effects from either jabs - what does that say about me as a person (medically)? ;)
In other vaccine news, typical that I get offered to do a vaccine trial the day after I've completed my full course of Pfizer! Not eligible to participate as I've been jabbed. Valneva – UK COVID-19 Vaccine Study Opening Now |
Originally Posted by lwildernorva
(Post 33267323)
I'm intrigued as an American who has had no problem with where the science has guided us and who has no education or experience to guide me otherwise. But I noticed that you (and others in the UK) definitely encourage a wider spread between the two-shot vaccinations than we have in the US. I've simply followed the recommendations here but am interested in the perspective from your side of the Atlantic.
What advantages are there that you see to the wider spread between the two shots? Less need for a booster shot later? More efficacy to lessen the serious effects or mortality rates? Interesting to me because it seems there's a definite difference in philosophy between the protocols. I just want a safer world to move around in. |
Looks like targeted call ups for 33 year olds in London now. Lucky devils are getting Pfizer too.
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Originally Posted by Swanhunter
(Post 33268138)
Looks like targeted call ups for 33 year olds in London now. Lucky devils are getting Pfizer too.
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Originally Posted by stut
(Post 33267822)
AIUI the original thinking was simply that, with the levels of virus in the community at the time and level of vaccine supply, it was more beneficial to give the maximum number of people one dose, rather than prioritise second doses after a shorter space of time.
Originally Posted by Schwann
(Post 33267935)
There was a recent study from Birmingham University that concluded that the antibody response was 3.5x higher for a group of over 80s that had the 2nd dose after 12 weeks compared to just 3. I assume that would be similar for other age groups but certainly seems like the longer gap between doses paid off.
https://twitter.com/sailorrooscout/s...65901764210691 |
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