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Originally Posted by narvik
(Post 34079064)
I am already booked on a PVG-AKL flight (in J, with miles....for cheap! lol) ----> that is Plan A....what I am after now is Plan B! :)
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Originally Posted by travelinmanS
(Post 34078600)
Just got the notice sent to my wechat at 4:30am. My community in Shanghai is now under lockdown. The gates went up in front of the compound right after and we all need to take 2 tests within 48 hours before we are released. I doubt that we will be released then however as I don’t see the spread of Omicron stopping and I’m hunkering in for a long incarceration.
Now I can sit alone in my thoughts as I watch my Chinese tech stocks collapse! Definitely is stepping up the timing of my exit plan. https://cimg5.ibsrv.net/gimg/www.fly...968117a304.jpg As I left my place, I noticed lots of testing sites with the requisite snowmen along Yongjia Rd. https://cimg5.ibsrv.net/gimg/www.fly...bfcfd3c216.jpg And also many policemen. I realize this picture doesn't convey such; I'm a little shy wrt cop photos. https://cimg1.ibsrv.net/gimg/www.fly...86ab55912f.jpg But in-person dining is definitely still happening at most restaurants here. As I mentioned yesterday, Jing'an has cracked down hard on this. https://cimg4.ibsrv.net/gimg/www.fly...dba391a623.jpg This is a picture of Nanjing Rd. facing east towards Jing'an Temple, which you can see on the left side of the street if you look hard enough (it is gold). I was amazed that there weren't any cars at all. (It is one of the busiest streets in Shanghai.) https://cimg9.ibsrv.net/gimg/www.fly...3e3a453e04.jpg After about 45 minutes of walking, I reached my goal, Will's Lobster. This is the menu. https://cimg6.ibsrv.net/gimg/www.fly...1e89233944.jpg And this is the product. I had low expectations because I grew up eating the real deal. However, I must say that it was pretty damn good. A little smaller than what I regard as standard, but Y93 would be a good price even in Boston. https://cimg3.ibsrv.net/gimg/www.fly...31be875b13.jpg At some point during my walk the lockdown notice showed up in my WeChat. It instructed me to go to the elementary school next to my compound. The process wasn't so bad. Now I'm back home. The deal is I can get my second test (also a throat swab, I think) at 10a tomorrow morning. And, once the result comes back, I'll be in the clear. The testing people told me to stay home, and I will. However, in my case, nothing would prevent me from fleeing (i.e. the gates are not locked). I would simply feel stupid if I flaunted this rule and got busted. I'm guessing I would stick out like a sore thumb if I wandered about because it appears that they've tested pretty everyone they could in this district. I mentioned all of the snowmen and police in Xuhui. I didn't see any in Jing'an. So, my theory is that they're moving around from district to district. I don't completely see the point of this exercise, but there are lots of things I don't understand about China. All in all, I don't feel particularly inconvenienced though. I'll just pretend tomorrow is a rainy day (even though it won't be). |
Quite an eventful day, Moondog.
Our compound is completely locked. We can go outside, use the tennis court, gym, etc. but just can't leave. But when I left to get testing, no one was following me so I walked around a bit and got a coffee. The concern now is the backlog of tests and how that impacts our release timing. |
So I am realizing there are different levels of lockdown. I guess to some extent it is the honor system whether someone "just goes to get tested" when they leave their house. And even in locked down places some eateries are open?
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Originally Posted by narvik
(Post 34077104)
So, it's starting on March 21st (not 17th, as everyone had predicted):
Flights to Shanghai from abroad to be divertedMore than 100 international flights to Shanghai will be diverted to one of a dozen different domestic airports beginning March 21 to help relieve the city's recent COVID-19 prevention pressure.The 106 flights to be diverted are on 22 routes operated by five domestic airlines – Air China, China Eastern, Shanghai Airlines, Juneyao and Spring, the Civil Aviation Administration of China ( CAAC) announced on Tuesday. https://www.shine.cn/news/metro/2203153131/ May be the diversion won't impact the inbound cargo flight. |
Originally Posted by gudugan
(Post 34075229)
Good analysis. Option 1 isn't feasible. The data was just released from late 2020 phase 1 trial of ARCoV (domestic mRNA vaccine) and phase 3 is not released/keeps getting postponed. Basically, it's highly likely that ARCoV doesn't work for Omicron (if it works at all). https://www.thelancet.com/pdfs/journ...21)00280-9.pdf They can't get enough Moderna/BioNTech even if they wanted to (politics notwithstanding) and distribution will take a long time.
https://cimg4.ibsrv.net/gimg/www.fly...67e7605f14.jpg https://www.nature.com/articles/s41422-022-00626-w |
Originally Posted by boat stuck
(Post 34081827)
ARCoV will just need a third shot for Omicron, same as Pfizer and Moderna. There's no data indicating that it'll be significantly worse than the other two mRNA vaccines (which still aren't great) against Omicron after a booster.
https://www.nature.com/articles/s41422-022-00626-w |
Originally Posted by gudugan
(Post 34081868)
I have no interest in playing armchair virologist but the article you linked says they only tested this in mice not humans. Manufacturing and distribution is still a problem.
Now you're claiming you "have no interest in playing armchair virologist" when confronted with contrary evidence. |
Yes, if there's no large-scale test data on humans we have no definitive answer if it works.
I didn't know about the article you posted. The original link I posted was data from late 2020 (released this month) when no one even knew Omicron existed so it's unclear if that formulation works for Omicron. The phase 3 data from ARCoV still hasn't been published to my knowledge, and your article says at the end ARCoV-Omicron is approaching clinical trials, so there also isn't any data there either. Note also in the phase 1 ARCoV trial they didn't even try it on anyone over the age of 60, which should be the target population. Developing a mRNA vaccine is nontrivial especially in China because they can't license the IP from other companies and have to do everything from scratch. It's not similar to an inactivated vaccine like Sinovac where the technology is well known. |
Originally Posted by gudugan
(Post 34081986)
Yes, if there's no large-scale test data on humans we have no definitive answer if it works.
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Originally Posted by boat stuck
(Post 34081827)
ARCoV will just need a third shot for Omicron, same as Pfizer and Moderna. There's no data indicating that it'll be significantly worse than the other two mRNA vaccines (which still aren't great) against Omicron after a booster.
https://www.nature.com/articles/s41422-022-00626-w And why quote a mice study, as nobody cares about those. Alzheimer's has been cured in mice. Care to tell me which drug is available for humans? |
People, please, lets keep this thread clear from COVID related details. 🙏
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Originally Posted by s0ssos
(Post 34082016)
In science nobody says there is 'no data' to prove it is worse. You do not presume non-inferiority. You have to prove it.
And why quote a mice study, as nobody cares about those. Alzheimer's has been cured in mice. Care to tell me which drug is available for humans? That was a response to: "Basically, it's highly likely that ARCoV doesn't work for Omicron (if it works at all)." I was pointing out that he presented no support for that assertion. In fact, the Lancet study and the more recent Cell study suggest the opposite, that ARCoV is likely to be broadly comparable. Given how recent Omicron is, it makes sense that mice results are the first available, and they look promising. |
Originally Posted by boat stuck
(Post 34082079)
That was a response to: "Basically, it's highly likely that ARCoV doesn't work for Omicron (if it works at all)."
I was pointing out that he presented no support for that assertion. In fact, the Lancet study and the more recent Cell study suggest the opposite, that ARCoV is likely to be broadly comparable. Given how recent Omicron is, it makes sense that mice results are the first available, and they look promising. India has developed a mRNA vaccine (Gennova), and it would be interesting to see how that compares. They are running trials. One question I have for the trials for ARCoV is how will they get enough patients? I'd presume most in China are already vaccinated. It is easy enough to find unvaccinated patients in the West, but they obviously won't volunteer. |
Originally Posted by UA_Flyer
(Post 34080721)
Not sure if you have looked into the UA 858 PVG-ICN-SFO. I flew on Feb 28 when UA 857 was not carrying passengers (just cargo). The oubound flight from China to the US can still carry passengers.
May be the diversion won't impact the inbound cargo flight. UA/AA/DL stay at PVG. |
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