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-   -   Local lockdowns in the UK (https://www.flyertalk.com/forum/u-k-ireland/2025295-local-lockdowns-uk.html)

paulaf Jan 25, 2021 12:14 pm


Originally Posted by HB7 (Post 32993705)
It appears as though the Moderna vaccine is effective against the SA and Brazil strains, according to Moderna, however the UK won't receive any of those vaccines till April.

The worrying thing however is the supply it seems. It is clear that the UK has the capacity to vaccinate well over 500k people a day, but supply might be an issue. If supply becomes increases significantly, or at least if we get another two suppliers (possible if J&J and Novavax trials are successful), then I think we could easily vaccinate 4 - 5 million per week.

Only 220k today though must be the weekend effect, maybe the snow caused a blip?

fransknorge Jan 25, 2021 12:35 pm

Do not confound vaccinate vs inoculate a shot. A vaccination requires two inoculations.

HB7 Jan 25, 2021 2:03 pm


Originally Posted by paulaf (Post 32993742)
Only 220k today though must be the weekend effect, maybe the snow caused a blip?

Yeh I think you're right. Last Sunday (18th Jan) it was 208k I think. So it seems like less vaccinations happen on Sunday generally.

plunet Jan 25, 2021 2:59 pm


Originally Posted by paulaf (Post 32993742)
Only 220k today though must be the weekend effect, maybe the snow caused a blip?


Originally Posted by HB7 (Post 32994023)
Yeh I think you're right. Last Sunday (18th Jan) it was 208k I think. So it seems like less vaccinations happen on Sunday generally.

I would imagine 4 significant vaccine centres being closed in Wales yesterday due to snow would have assisted in reducing the numbers.

HB7 Jan 25, 2021 3:15 pm

From the Mirror: Hotel quarantine plans 'will stop Brits holidaying abroad for a year', experts fear

https://www.mirror.co.uk/news/uk-new...658#r3z-addoor

ahmetdouas Jan 25, 2021 3:28 pm


Originally Posted by HB7 (Post 32994184)
From the Mirror: Hotel quarantine plans 'will stop Brits holidaying abroad for a year', experts fear

https://www.mirror.co.uk/news/uk-new...658#r3z-addoor

It's getting better.
Now Dailymail saying Brazil and SA hotel quarantine to be implemented first with the rest coming later, I guess this is to keep the fear factor level high!

​​​​​​https://www.dailymail.co.uk/news/art...ine-plans.html

Also the vaccine war is really starting to get ugly, EU threatening to block exports of vaccines (this will hurt UK for Pfizer, not Astra as that is mostly made in UK) and Germany claiming Astra Zeneca only 8% effective over 65's and Astra Zeneca denying this completely. Pfizer looks like amazing results on the field in Israel.

stut Jan 25, 2021 3:31 pm


Originally Posted by HB7 (Post 32992707)
Good bye 2021 travel and likely a significant amount of 2022. Seems like government is intent on killing off the travel and aviation industry.

As someone who lost his job in the travel industry last year, I can confirm that it was very much already in tatters before the talk of quarantine hotels.

(I have a new job, btw, different industry...)

HB7 Jan 25, 2021 3:36 pm


Originally Posted by ahmetdouas (Post 32994215)
It's getting better.
Now Dailymail saying Brazil and SA hotel quarantine to be implemented first with the rest coming later, I guess this is to keep the fear factor level high!

​​​​​​https://www.dailymail.co.uk/news/art...ine-plans.html

Also the vaccine war is really starting to get ugly, EU threatening to block exports of vaccines (this will hurt UK for Pfizer, not Astra as that is mostly made in UK) and Germany claiming Astra Zeneca only 8% effective over 65's and Astra Zeneca denying this completely. Pfizer looks like amazing results on the field in Israel.

Germany claiming AZ/Oxford only 8%?? LOL - we always knew these political games were going to happen. It'll be interesting to see how it plays out.

HB7 Jan 25, 2021 3:40 pm


Originally Posted by stut (Post 32994227)
As someone who lost his job in the travel industry last year, I can confirm that it was very much already in tatters before the talk of quarantine hotels.

(I have a new job, btw, different industry...)

Incredibly sorry to hear that. It's a real shame, particularly as the government has hardly consulted with the travel industry when it makes decisions. Heathrow begged the government to look into testing for months - and the government completely ignored it, and now look where we are.

They just make up rules as they go, often based on nothing. It's a shambles and its people like you in the travel industry who have already lost their job or are about to.

Internaut Jan 25, 2021 4:32 pm


Originally Posted by HB7 (Post 32994235)
Germany claiming AZ/Oxford only 8%?? LOL - we always knew these political games were going to happen. It'll be interesting to see how it plays out.

Well Britain bet the farm on AZ/Oxford. I guess we’ll know in 8-10 weeks...

KARFA Jan 25, 2021 4:38 pm


Originally Posted by Internaut (Post 32994355)
Well Britain bet the farm on AZ/Oxford. I guess we’ll know in 8-10 weeks...

so did the EU. It ordered more AZ vaccine than any other one.

tbh the report is extremely suspect. Unless the MHRA in the UK has made the biggest error ever, the data clearly shows much higher effectiveness than 8% in over 65s. Had it been that low it simply would not have been approved for that age segment.

From the point of view of Germany and others in the EU, I suspect their time would be better served asking why the EMA is taking so long, as of two weeks ago they hadn’t even started the approval process for the AZ vaccine.

HB7 Jan 25, 2021 4:49 pm


Originally Posted by KARFA (Post 32994366)
so did the EU. It ordered more AZ vaccine than any other one.

tbh the report is extremely suspect. Unless the MHRA in the UK has made the biggest error ever, the data clearly shows much higher effectiveness than 8% in over 65s. Had it been that low it simply would not have been approved for that age segment.

From the point of view of Germany and others in the EU, I suspect their time would be better served asking why the EMA is taking so long, as of two weeks ago they hadn’t even started the approval process for the AZ vaccine.

In addition to this - why the EU took so long to approve the pfizer vaccine as well. The vaccine was in part developed in Germany by BioNTech, but it took the EMA 3 weeks longer than the UK and 10 days than the US to approve it.

ahmetdouas Jan 25, 2021 5:17 pm

COVID is getting really political really fast. California lockdowns released after Newsom is in trouble, no longer stay at home order. I wonder if something similar will happen in the UK with regard to lockdowns. And the Netherlands has a 3 night in a row riot scene due to its curfew (still never understood the point of a curfew during lockdown, its not like you can go clubbing!)
The data is looking good though and it is winter, so I don't see too much activity before early March, but the Times is rumouring Primary schools to start again after 15 Feb.

Also yes the data doesn't make sense, yes you can have differences in effectiveness over ages but suddenly collapsing to 8% with the same vaccine just because you are older? Come on now.

fransknorge Jan 26, 2021 12:54 am


Originally Posted by HB7 (Post 32994235)
Germany claiming AZ/Oxford only 8%?? LOL - we always knew these political games were going to happen. It'll be interesting to see how it plays out.

No Germany does not claim that AZ/Oxford has 8% efficiency. An article published in the Handelsblatt report the efficacy of the AZ/Oxford vaccine over 65 yo is 8%, claiming anonymous sources in the federal government.



Originally Posted by ahmetdouas (Post 32994437)
COVID is getting really political really fast. California lockdowns released after Newsom is in trouble, no longer stay at home order. I wonder if something similar will happen in the UK with regard to lockdowns. And the Netherlands has a 3 night in a row riot scene due to its curfew (still never understood the point of a curfew during lockdown, its not like you can go clubbing!)
The data is looking good though and it is winter, so I don't see too much activity before early March, but the Times is rumouring Primary schools to start again after 15 Feb.

Also yes the data doesn't make sense, yes you can have differences in effectiveness over ages but suddenly collapsing to 8% with the same vaccine just because you are older? Come on now.

I am sure you have a strong argument based on immunology to affirm age does not impact an adenovirus vectored vaccine efficiency significantly ?


Originally Posted by KARFA (Post 32994366)
so did the EU. It ordered more AZ vaccine than any other one.

tbh the report is extremely suspect. Unless the MHRA in the UK has made the biggest error ever, the data clearly shows much higher effectiveness than 8% in over 65s. Had it been that low it simply would not have been approved for that age segment.

From the point of view of Germany and others in the EU, I suspect their time would be better served asking why the EMA is taking so long, as of two weeks ago they hadn’t even started the approval process for the AZ vaccine.

The German government is actively asking the EMA the reason for delays. They pushed the agency to approve the BioNtech vaccine earlier than expected already.
https://www.politico.eu/article/germ...ore-christmas/

Gagravarr Jan 26, 2021 1:48 am


Originally Posted by HB7 (Post 32994392)
In addition to this - why the EU took so long to approve the pfizer vaccine as well. The vaccine was in part developed in Germany by BioNTech, but it took the EMA 3 weeks longer than the UK and 10 days than the US to approve it.

Is it something to do with the kind of approval?

IIRC the Pfizer vaccine was initially just given batch-by-batch approval, before later getting a general approval. I believe that the Oxford / AZ vaccine is still on batch-by-batch approval in the UK (including with some batches getting rejected, which makes the supply chain lumpy), until their GMP / QA gets the nod to do all the checking themselves so they can move to full approval.


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