I've had my checked bags opened when transiting through MIA and ORD on international-international and both times notes were left. This was in August and December last year.
I guess checking in a backpack with two laptops in it raised some suspicion
No. Too much density IMHO to see anything clearly on the x-ray machines. I've travelled with 3 laptops and a tablet in my carry-on , nobody ever got suspicious when I started unpacking them.
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We knew they went through one of our bags by leaving a "present" - A big heavy duty box cutter. Definitely wasn't ours, found it when opening the suitcase at home.