I use Trend Micro's PC-cillin, and so far I like it. It does everything that Norton does, but does not annyo me as much as Norton (such as no subcription fees). The 2002 version I have is regullarly updated which is a plus, and it always caught whatever virus came my way. I like the fact that you can send a report to Trend Micro about a quartined virus, and they will email you back rather quickly about how you can remove it.

Ive cant say much about McAffee, since ive always have had issues with their products. There is also AVG Antivirus, which is the best free antivirus available (I think updates are every other day).