There was no master thread for this hotel yet, so I figured I'd create one and write a quick review.

Check in was smooth, very nice staff, no issues despite the hotel still being very new.
There are no suites, but we got a nice room on a high floor that had views of a parking lot, with the Sagrada Familia in the background.
The hotel is brand new and has quite a nice, modern design. The doors were very thick, so I don't think you'd hear any noise from the hallway.
As I am a Titanium Elite member, we received drink vouchers for the rooftop bar that were good for soft drinks, beer, wine or cava, if I remember correctly.
There's a small rooftop pool as well, but it wasn't warm enough that we felt like hopping into it (and it's VERY small, it's not like you'd be able to really swim there).
The area immediately around the hotel is quite boring, it's mostly residential buildings, but restaurants are just a 10 minute walk away.
There's also a restaurant in the hotel (Alcachoa, on the lower floor), which we didn't check out, apart from the breakfast that was served there.
Breakfast was served à la carte - not sure if this was due to there being so few guests (there were at most 3-4 other guests having breakfast at the same time as us), or if this is a permanent thing.
The breakfast was OK (probably very good by Spanish standards), though I pitied the servers who were constantly running from table to table and seemed a bit overwhelmed, despite there being so few guests.

We booked this hotel mostly because of its gym, which looked great in the photos (two proper squat racks/power racks!).
Unfortunately, while it looked great, the quality was rather cheap. For example, the weights on one side of the cable tower would often get stuck during exercises (already mentioned to the staff, as this will hopefully be covered under warranty). Another issue was that the lightest plates they had were 5kg, so you could only increase the weight on the barbells by at least 10kg at a time. Gave them feedback on this as well, hopefully they'll order more plates.
It generally didn't seem like the gym equipment was ordered by someone who is actually into weight lifting, but hey, I guess I shouldn't complain as many gyms don't have any barbells at all.

All in all, it was an OK stay and I would stay there again. The Four Points (which I liked a lot for its price and location) is just a 5-10 minute walk away - though the gym at the Four Points is a complete joke with just some treadmills, a single bench and some dumbbells.
I would stay at Labtwentytwo again, but then again, there are so many hotels to choose from in Barcelona that I'd probably book something else next time, just to try it (I've mostly stayed at the W in the past because of its location on the beach and nice pools).

Uploaded some photos here (including a photo of the breakfast menu):
https://www.directupload.net/galerie/526481/2sG7pRZ9BV

Let me know if you have any questions.