We always pick 1B/C. I pick 1C for a daytime flight (like yesterday's SFO-JFK) because I know +1 will be sleeping in 1B and I appreciate not getting bumped as much with the console between me and the aisle. Yes, there's a bit of noise from the lavs but with headphones on, it's not intrusive. Meals will be first out of the galley and one can take advantage of a post-meal lav break while others are still eating.

The larger footwells are the only ones that allow me any comfort and I only wear size 10 shoes.