Originally Posted by
SJOGuy
I'd say base yourself in Antigua the whole week. Don't even bother with Guatemala City except for the airport. The capital is a big, noisy city without much to see or do. Antigua is the old colonial capital. It has charm and style and wonderful small inns and a great dining scene and lots of tourist sights. Antigua actually makes a better base for exploring. On the Thursday or Sunday you're there, you can go to the market in Chichicastenango, about two hours away. It's touristy, but I always find it to be great fun too.
Chichicastenango is fascinating. I went once many years ago on a day trip from Antigua and would love to go back and spend a night or two in the town as well.