Sometimes, depending on a lot of factors including time zone differences, flight times, departure times, arrival times, ability to sleep on flight, ability to sleep at appropriate time at destination.

For time difference of up to 3 hours, usually no jet lag.
West Coast to Europe is tough. The 8-9 hour difference is hard to deal with, sometimes not right away but a couple days later.
Westbound is generally easier for me, just makes for a long day.
West Coast to Hong Kong was surprisingly easy, since we left in the morning, arrived in the evening and were able to have dinner then sleep at a reasonable local time.