Originally Posted by
plunet
The science based podcasts I have been listening to seem to infer that whilst the manufacturers were looking to do an update to the vaccine based on specific variants previously, what seems to be more under discussion recently would be a general vaccine update that wouldn't be specific to variants but can 'train' the vaccine to create immunity that can look for a broader signature of the virus and the ways mutations could and are likely to develop over time. I think I understood this might make the focus of the detection move away from the spike protein as this is likely to change with each mutation but I might have misunderstood that point. And I'm not a virologist!
That would be a smart approach, although viruses have a habit of changing just enough in the right places to undermine sciences best efforts. In addition, if the next virus is as weak (in causing health effects, in general) to Omicron as Omicron was to Delta/Delta+, then the law of diminishing returns might start to become a factor here.
rb211.