Definately. I'm staying at Courtyards, Marriotts, JWs, and Renaissances that I would not have done when it was just SPG.
Courtywards in Asia (Taipei Downtown, Iloilo, HK, Sha Tin) are great value with lounges, breakfast, suite upgrades at some, evening food and drinks. Full service. I find them better than Four Points because of the lounges.
New Marriotts (HK Ocean Park, Shenzhen Nanshan) are great hotels with good recognition and lounges. Old ones are indestinguishable from legacy Sheratons.
JW (KL, HK) and Renaissance (Shanghai Yu Garden) are solid hotels though I don't find the brands to be particularly distinctive for the prices (much like Sheraton Grands and Westins).
I don't stick to one brand but tend to stick to around the same rate of US$120-150 inc taxes etc. So that determines where I look in a particular city. The merger has expanded my footprint of available hotels.