This fare can be twisted in a lot more ways than people seem to think so. Can be used for any travel to South America up to and including SCL.
Can also go as far south as JNB using some odball carriers (on this itin, like LH or TK). Can be all OW of course if that's needed.
One key seems to be going beyond GRU for the 1850 extra miles one gets by flying through instead of terminating. Can be substituted by flying through Lima but that won't do much good for most I'd guess.