Wyndham Beacon Hill Boston. Just finished a 3 night stay. Excellent location. Read some TripAdvisor reviews that some of the rooms were tired, but we called the property and paid extra $18 per night for upgrade to Executive King on 12th or 14th floor. Nice king room. View of Charles River and Beacon Hill. Traveling with picky wife, no complaints from her, nuff said.
Starbucks across the street on Cambridge St. Whole Foods, CVS and wine store , out the back door. Mass General Hospital next door.
Liberty Hotel , SPG Luxury Collection about 3 blocks away.