Interesting essay on the effects of severe jet lag in the NY Times Magazine today, 03/07/04. It's taken from a forthcoming book, "Sun After Dark: Flights Into the Foreign", by Pico Iyer.
You can access the article online here -
http://www.nytimes.com/2004/03/07/ma.../07JETLAG.html - requires a subscription (free).
He does a good job capturing the surreality of the jet lag experience. Worth a read, IMO.