If Doug repeats what he did with US Airways, focusing on hub flying, BOS will be the first sign of it - goodbye ROC, BUF, SYR, MDT, and the Caribbean. I wonder how profitable BOS-Caribbean flying is with the new airline's higher costs and jetBlue competing on the route, especially with B6 about to add more seats in their planes (more seats = lower costs).
BOS is not required to maintain any level of flying per the DOJ settlement, so cutting (what are likely) unprofitable legacy express routes and leisure routes to the Caribbean is not a difficult task.
BOS-CDG is the only one I truly wonder about - it is the only TATL flight AA flies that does not touch a real oneworld hub on either end (BOS is a US focus city at best), is seasonal against year-round Skyteam flights, and yet they are expanding the seasonality of it by 2.5 months in 2015.