In a trip report I posted back in September, I noted a low level vibration on the 380 seat 53a that stopped me sleeping. I did assume at the time that it was coming from the plane rather than my seat neighbour.
"I settled down for sleep. I don't know if it's my location or general for this area but there is a low freq vibration that becomes very disturbing when you put your head down. This really prevented me having a good nights sleep. I've not noticed this on other flights so don't know if it's specific to the 380. It's not because it's quiet as this is a vibration that ear plugs don't stop. Other than this the bed was comfortable and private. I didn't notice noise from the galley when I had ear plugs in. I also had no problem with cabin temperature, a apparent issue on some of the 380s. I managed a few hours of sleep, but I never sleep very well on planes so this was as good as I could expect."