Originally Posted by
KLouis
On the other hand, a Freccia in the morning with arrival in Rome in the early afternoon would be no problem. And there will always be taxis at Termini.
This is precisely what I meant - leave Venice in am, after breakfast. But definitely the OP should reserve tickets in advance.
There is, however, no way I would arrive in Rome on Easter Sunday - and I speak the language/understand the bus/metro system.