I've done similar many times. If you stick to interstates, driving I-70 west of Denver to Nevada will be the highlight. I-40 has less to offer unless you get off it from time to time.

If you pay attention to the landscape it changes radically as you head west, always getting drier and drier as the trees thin and shorten. It surprises me that people find long distance driving dull in the USA since there is always a lot going on visually even through the flattest bits (as opposed to say driving across Australia which is breaktakingly dull).