Drunken packing for the return home is just as bad, if not worse.
I had a night in Tokyo last year, where a very senior boss took me out for sushi and beers. I had to get up at 4am the next morning to get to New York, but I didn't want to appear ungrateful, so stayed out far later than I should have done and drunk too much too. When I finally arrived home I was still worried about what I might have left behind.