I use MP3 players a lot since I listen to a lot of audiobooks. I have two iPods, two Sony walkmans and a Zune. The iPods I don't use very much since my PC doesn't play well with iTunes. The Zune I also avoid since it has a very complicated loading system and a very short battery life, although it does have the best all around sound. My favorates are the two Sony Walkmans which are easy to load, easy to use, and have longer battery lives than either the iPods or the Zune.
I haven't tried any of the Sansa models yet, but will try one for my next purchase.