Chase doesn't care how much you spend at office supply stores. That's why they have the $50,000 cap on 5x annual spend.

Also, you don't need a 5x card at drug stores to match the "deals" at Staples/OMax/OD.

Consider:

$34.75 to manufacture 5000 UR points. = $.695/point
$7.90-$11.90 to manufacture 5000 TYP/MR points. = $.158-$.238/point

Even if you're one of those people that "value" UR points at 2x or higher, generating points at grocery stores or drug stores is 3-4x cheaper than drug stores, for people that have cards that give 5x spend at grocery/drug stores.

I have a card that gives me uncapped 3% rewards at grocery stores all the time (PenFed). Anyone can get it, if they wanted to.

$11.90 to manufacture 3000 points = $.4/point, which is STILL cheaper than going the UR route with the Ink cards.