If you are GETTING miles back... then go to first.
If you are taking Mrs. Toad then by all means UPGRADE AS FAR AS YOU CAN GO!!!! It can make a very nice impression on that special lady, showing you care enough to use your miles for her! It's a sign of true love and she'll thank you for it!

(I should know!)
Otherwise as My BIG BRUDDAR PREMEX and others have said: Business is just fine. I'm sitting there on my airline U-A (and it was worth the 20K miles, if only I can do some work and relax and hopefully sleep a bit before work work work

in LONDON.)
I could not see myself in coach for 6-7 hours so it was worth the miles.
OMNI for Traveling TOAD: while in your AA plane skip all the free champaigne and Devars and go for the best stuff on earth: PEPSI!!!!! (in honor of your buddy the Cat eating your Bern's steak in Tampa!)