Dreamliners on the Manchester's will make economic sense as the airline does have difficulty filling the C30 Y275 configuration 333's that currently ply the route
Whilst the Dreamliner is a better fit for the route, don't be fooled on how a route is performing based on what you
can see. Qatar makes a ton of money on the bit you
cannot see, the cargo. That is
part of the reason an A319LR was a definate no-go for Manchester. (I know range is a slight issue too, but, it was mostly lack of cargo which sealed the decision)
Also, as reported elsewhere, loads on both QR flights have been in in the 80-90% avarage range for 2-3 months now, reflected in the fact the slightly larger A330-300 is used more than the A330-200 lately too.