I've been thinking about this for a while.. a way to get in to northern South America and the Caribbean from a southern airport that doesn't have direct service to many of these destinations, with some feed from current F9 hubs/focus cities and some other northern and Midwestern cities.
Call me crazy or a dreamer.. but I think these routes utilizing RSW would be interesting. Cough up a codeshare on Air Berlin to DUS.. to spice things up a bit. Maybe one with Cape Air to EYW..
The range circles are as follows: Q400, E190LR, E190AR(ex-US Airways), and A319-100.
Unfortunately, the money and the metal isn't there.