I'd guess that when you include a QF trans-US leg in an OWE you'll find rate agents that say "absolutely not" and others that agree that it's a fine thing to do, i.e. you may have to argue with someone or hope for an enlightened supervisor. Most likely, you'll have no problem. FT'ers have certainly used the route, and I don't recall any post by someone saying they'd been denied. And it shouldn't matter how you insert it into your rtw.