Malaria not only kills 1 million people, mostly children, a year, but causes financial havoc on places that least can afford it.
As a responsible traveler and someone who is quite close to prominent virologists working in sub-Saharan Africa, I have to ask myself when I go if I'm being a responsible traveler if I don't take meds in malaria-infected areas. If I get malaria and an uninfected mosquito bites me, that mosquito may now contract malaria from me and go on to infect others - including those who can't get the same level of care that I can.