How you configure your cache depends a lot on where you're browsing from and what you're looking at.

For instance, if you're on a dialup connection, you probably want to keep caching turned on, so that you don't have to keep loading in new pages on a 56K connection.

If you're on a broadband connection, though, it might benefit you to turn your caching off and have the page pull a new version from the server each time, since download time is probably minimal.

If you're browsing a frequently updated bulletin board, like ours, you may want to turn your caching off, regardless, so that you're sure to get the newest version of a thread.