Out of curiosity, I just checked the known places to which I will travel between now and 12-31-10. Only one SPG hotel conveniently located close to where I work. Looks like I will stick with the Hampton's and Garden Inns.
I just upgraded from Choice Hotels (located in industrial areas as well) and I am thoroughly satisfied with HH. Even if you get points with Choice, they are only usable at Comfort Suites or similar or worse, not a great perk. The up scale properties they offer are nearly impossible to book with points. HH has been good to me so far.