Originally Posted by ArizonaGuy

The problem with a thread for using any miles across any alliance is that it would be gargantuan and eventually no one would read it entirely. Every airline has their own rules and requirements for using miles and they're large enough as it is (See US Airways Award FAQ thread as one example.)

There's generally a thread in each airline forum that has discussion of the best way to use that particular airline's miles within the rules they have laid out.

If you indicate where you want to go and in what class of service - coach, business or first, and maybe even your rough mileage account balances, we could probably point you to your best option. Obviously not all alliances or airlines fly everywhere.