No. NEXUS and GlobalEntry are two separate programs, administrated separately.

For the purpose of air travel, NEXUS is a program run out of Canadian airports only. There are U.S.-based enrollment centers, but most do not have the iris scanning equipment that is necessary in order to qualify you to use the passport control kiosks at Canadian airports. So, in most cases, you would need to schedule an appointment at a Canadian airport enrollment centre in order to join the program.

GlobalEntry is a wholly U.S.-based system, run out of offices at U.S. airports.

You can apply for both NEXUS and GlobalEntry via GOES. If you plan on joining both, I recommend applying first for NEXUS, which is $50 for a 5-year membership. Upon acceptance into the program, you will have been vetted by both Canadian Customs and US CBP, and confirmed as a "trusted traveler" by both. Then, if/when you decide to apply for GlobalEntry, you most likely will get automatic approval, since you already completed the CBP interview and digital fingerprinting that would occur at the GlobalEntry interview.

Also, if you are already a NEXUS member, then GlobalEntry membership is FREE! So, you get 2 programs for 1/3 of the cost! ($50 instead of $150)