Window>Aisle>Middle.
I'm unfortunately a lowly silver with Asiana so I never get exit row or bulkhead but I get to lean against the wall if I ever feel like dozing off (I can never get any kind of deep REM sleep on airplanes) and I'm lazy so getting up for people is obviously a pain in the butt. The only time I ever use the bathroom on airplanes is if I'm flying a foreign carrier. US carriers' bathrooms are disgusting. I'm always scared that I'll catch something if I go in there.