Surprised no one mentioned several issues with the aisle seats:

1. The flight attendant opening soda cans and spritzing the nearby aisle inhabitants
2. Passengers boarding with various carryons that bash you going down the aisle. Worst case is the backpack that smashes you in the face when the passenger turns in the aisle to look at space in the opposing overhead. Unless you count the time the passenger bend over to get something off the floor across from you, sticking large _____ in your face.
3. Passengers dropping stuff out of the overhead above you.
4. Passengers using your seat as a hand hold to pull themselves forward, then releasing it suddenly to launch you.

Mrs. Blue47 puts up with this so that she can easily use the lav. Not me.