pgolier summed it up rather nicely.
Re: your specific question re: Burbank activity on the weekend, no not really.
Studios in LA are in different locations: Warner & Disney in Burbank, Fox in Century City, Sony in Culver City, Paramount in Hollywood, Raleigh in Hollywood & Manhattan Beach, and post houses & supporting sound/editing, etc, facilities are all over the place as well, which is why pgolier is correct in stating that you could be doing a lot of commuting.
Cheers.