If your wife is a CA in the UK, then she just needs to take a reciprocity exam to get her CA in Canada (look at the ica.bc.ca website since you apply in your local province). CAs are currently pretty valuable and fairly scarce right now but, as always, it depends on your background and experience.

Vacation. Minimum is 2 weeks to start - most major places offer 3 plus statutory holidays (all of them have names, and most have meaning).

Vancouver is expensive housewise compared to average or median salaries. If you can sell in London and buy in Vancouver, you are likely laughing, but otherwise things are pricey given wage levels.