The former Air Force flight surgeon who is my MD suggested this, and it's worked for me -- especially if you're forced to fly with a head cold and your sinuses are already congested when you board:
1. Get some pump-mist nasal spray and some Neosporin.
2. Pump the mist before take-off, again during flight, and again just before descent.
3. Rub some of the Neosporin on your finger, rub it around the front of each nostril, and inhale.
The spray clears the sinuses; the Neosporin is an anti-biotic that helps prevent bacterial infection. It's the bacteria that bring on sinusitis and/or bronchitis.....