A funky choice is the Hotel Oregon located in downtown McMinnville (the county seat and with several winery tasting rooms now opened within staggering distance). Hotel is historic (100 year old and shows it, but renovated so should be OK). Otherwise it is only B&Bs and some motels in wine country at the moment (a bit of a vacuum for a higher-end hotel -- it isn't like Napa yet, but of course that is a big part of the charm).