You should sit where you want to. Not where you think some grumpy old man is less likely to complain. You paid for your tickets, not grumpy.
Personally I would go for the UD, if you can get 4 seats together, ie
63AB, 64AB or
63JK, 64JK
(which offer 4 seats seaparated from anyone else, plus some floor space at the foot of 64K, and even more floor space at the foot of 64A)
or
61AB, 62AB or
61JK, 62JK
(which offer a 4 seats together, and you don't have to walk over anyone, just whoever is in 61B/61J will have someone stepping over them, also you get loads of floor space by the emergency exits)