When I received my new laptop from work, I immediately purchased a second hard drive and installed it. My day-to-day, intra-US work is performed on that second hard drive. The original hard drive, with it's virgin installation of our corporate image, remains locked in my safe at home. It will be installed in the computer prior to any international travel.

It already has PGP and CCleaner installed, to permit the requisite cache deletion and free-space wipes prior to transiting Customs on my return.

I also carry a single 4GB Flash drive with me, in order to be able to work on customer-provided documents. That drive is also re-formatted and complete free-space wiped prior to returning stateside.