The eye candy is definetly better in SAN - and the weather is about the best in the country. The Hillcrest area is fun, relaxed and friendly.

There's the Blue Moon Resort in Vegas which is a true lesson in how to redo a motel into something special, as what they started with I am sure looked like the Vagabond Inn next door, and you can be at the pool naked, but for a few days to see something nice, I'd pick San Diego anyday..