I had a flight on AS back in 2002, IAD-SEA, and there were not one, but two screaming two-year-olds in their own row, on the 5hr+ flight. Granted, this was an anomaly, but it sure made for a long flight. The two FAs in first were also very upset that there were rugrats in front.

Still not as bad as a flight on DL I had a few years ago. As we were pushing back from the gate in CVG I hear this barking. I looked at the person sitting next to me and we were both speechless as this woman took a tiny dog out of her bag from under the seat. The damn thing didn't stop barking and yelping until we were somewhere over Montana.