1. A Q-UP is a discounted First (generally Domestic) fare. They are known on some airlines as Y-UPs (AA), on some as R fares (CO), and NW has strange fares that can begin with a K that book into F. I just use Q-UP as a catch-all, and even the airlines that regularly offer Q-UPs (DL & UA) also offer H-UPs, M-UPs, Y-UPs, etc. They all work on the same principle (discounted domestic F travel at far below full-fare rates). They are extremely useful mileage earners in some programs where you can earn up to 600% mileage bonus (if not more) flying one of those fares. Accordingly, one can often fly those fares at cpm (cents per mile) figures as low as those you would expect to find on a decent Y-class mileage run.

2. Mileage Run Deals Forum

3. Sure. I work full-time, go to school at night, and have maintained a long-distance relationship for four years (being able to travel every weekend helps immensely, in that regard). All the travel keeps me sane. Otherwise, the 80+ hours/week I spend working, attending class, and studying would drive me nuts.