old thread I see but I will throw in a few.
IAH-YEG (bring back Edmonton!)
IAH-MAR Maracaibo, a town I used to live in that has good Texas traffic, even in the Chavez days. If an agreement with the gov't could be reached.
IAH-Italy (Rome or Milan) hopefully with a 787 (I know folks would rather have Spain) this is just for me

IAH-FTW Houston to Fort Worth was tried by Mesa but Mesa had other issues I would love a few RJs a day into Meacham at Downtown Fort Worth avoiding Dallas and the transport issues completely, which is always a good thing
Just my fantasy .02
Ciao,
FH