The way you have to look at this is from an alliance viewpoint. There are only 3 alliances, so that's a start.
I'd say there are so many Skyteam and *A options that with a bit of flexibility you should be able to find something on either.
OW is not as good because there's only AA, BA, MA and IB you can choose from- the other two alliances have at least 8 different airlines (each) that fly the route.