In-n-Out will be the only thing I really miss about San Diego when I move away (whenever that may be).
The burgers are much tastier than something similar from other fast food joints of comparable price. Fresh lettuce, fresh tomatoes...with a bit of flavor to them, not like the limp leaves and mushy ooze of other places' "fresh" burger toppings.
Of course, I am currently finishing up my lunch of a Frostie and fries from Wendy's, so clearly, I am willing to eat anything if the price and location is right.