Welcome to FlyerTalk HotNsunnyNphoenix.

I always do. I've observed the Flight Attendants preparing them on numerous CO and HP flights and have no hesitation whatsoever. The prep I've seen involves removing the towels from their pre-packaged plastic wrapper, placing them on a tray, pouring a controlled amount of water on each one, microwaving them to near steaming temperature and immediately offering one via tongs to each First Class passenger. Although not surgically sterile, I'm comfortable with the operation.

Is there something I'm missing?

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