Our family (5 rooms) stayed at the Mecenate Palace Hotel - not too far from the Coloseum in a nice neighborhood overlooking a gorgeous church and plaza. Rooftop bar & breakfast room, lovely rooms with great bathrooms (best showers & towels of the trip!). I think we booked through Booking.com & the rate was E220 for a deluxe double, E165 for a Superior Double (not sure of the difference - might have been the view, as I didn't see the 2nd room). Excellent charming staff, lovely lobby - we really liked this hotel!