Not really, since TWA's main hub is St. Louis and his Holiness "flavored" his trip around St. Louis & midwestern themes. He even requested the Missouri governor have mercy on a convicted killer embarassingly scheduled for execution during his stay in St. Louis.

Although I'm guessing this is an OMNI reply, the convict who was sentenced to die will now serve life in prison.

Back to the subject, perhaps the Pope heard that the TWA flights are usually not filled and he'd have some extra room to move around. After all, the Holy Father is well-connected and it is a long flight to Rome.