Possibly, but I think that would mainly be on the outside of the can. The can should be a sealed system. So, at least my understanding is that altitude shouldn't affect the pressure inside the can as it's solid. On something like a balloon, sure, it would actually expand. If pressure is still an issue, I would think that the pressure would actually increase inside the can because the outside pressure would be lower, making it more likely to explode.

It's been awhile since I've taken chemistry/physics, so I could be wrong.

I have had cans make a mess as well, so I'd just baggie it.