I live in MSP, so it is the obvious choice. Good upgrade success, even as SE. Reward tickets - I've had good luck using miles at standard levels - a little flexibility on dates works wonders. 125% mileage match. Four or more rows of first class on every plane.

As GTITAN mentions about CLT, flying US is a traumatic experience in my book. I maintained status on NW and had it on US. After moving back to MSP, it is all NW all the time.